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 MSIA™

Mass Spectrometric Immunoassay (MSIA™) is a novel approach used for the rapid and accurate analysis of proteins residing in complex biological matrices. MSIA-tips are affinity pipettes that increase protein detection, eliminate extensive sample preparation, and are fitted for robotic workstations for sensitive, high-throughput, parallel sample analysis.

Proteins of interest are selectively retrieved with minimal non-specific binding. Analyses range from the confirmation of an amino acid sequence of a targeted protein to the detection of point mutations and posttranslational modifications. Ambiguities (false-positives/negatives) in analyses are eliminated in that targeted proteins are detected directly at exact and characteristic molecular masses. Downstream applications include protein quantitation, multi-analyte assays and the investigation of protein binding partners.

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